Isolation, Characterization and Evaluation of Anti-convulsant Activity of Rubus Antidiabetic Activity of the Plant Abutilon indicum in Streptozotocin Induced. Abutilon hirtum extract and fractions exhibited anti-inflammatory analgesic, antipyretic and antipyretic activities which may be attributed by the. Abutilon indicum Sweet is an Asia phytomedicine traditionally used to treat several disorders, including diabetes mellitus. However, molecular.

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Indexed in Science Citation Index Expanded. View at Google Scholar N. Thus, these results provide evidence that these compounds may lead to affect the antidiabetic activity of A. The findings of antidiabetic properties in this study are summarized in Figure 7and support the ethnobotanical use of A. The medicinal plants are widely used by the traditional medical practitioners for curing various diseases in their day to day actjvity.

Evidence-Based Complementary and Alternative Medicine

Subsequently, we found that crude extract of A. However, molecular mechanisms supporting the antidiabetic effect of A.

The differentiation media was changed every 2 days until day 4. Transfections and assays were performed in triplicate for each experiment group. The effect of crude extract of A. Present investigation includes examination of morphological and microscopic characters, antidiabteic value, extractive values and Phytochemical evaluations including qualitative chemical examination of active constituents were carried out.

The boiling process was repeated twice, and the combined extract was filtered across cotton wool and gauze.


In fact, impairment of insulin action has also been observed in syndromes including inflammatory and chronic infectious diseases in addition to type 2 DM [ 4 ]. The methanolic extract was subjected to anticonvulsant activity by MES induced epilepsy and determination of neurotransmitter concentrations in rat brain after induction of epilepsy.

The present study deals with the micro morphological studies carried out on the leaves of Cayratia carnosa, one of the World Health Organization WHO accepted parameter for identification of medicinal plants.

It purifies the blood and is given for hepatopathy, cardiac disorders, ulcers, wounds, dropsy, haemorrhoids and strangury. The results demonstrated that administration of A. A yield of turpentine from resin averaged was almost Traditionally the plant parts are used as sour, astringent and diuretic and is useful in conditions such vata, tumours, fever, neuralgia and splenopathy. Thus, we examined the possibility that the extract may stimulate glucose transport through a mechanism similar to insulin signaling in C2C12 myotubes and 3T3-L1 adipocytes.

The defective glucose transport system may play an important role in the pathogenesis of peripheral insulin resistance, and glucose uptake in target tissues is a critical step in maintaining glucose homeostasis and abutklon clearing the postprandial glucose load [ 45 ].

The needles being rich in resin content is a highly inflammable fuel for igniting forest fires. There exists a genetic predisposition to diabetes; however, environmental factors such as a sedentary lifestyle and obesity are the most prominent risk factors [ antidoabetic ].


These results suggest that the extract from A. We have reported that the phytochemical analysis of the whole plant extract revealed the presence of alkaloids, flavonoids, and tannins [ 11 ]. The present study involves the quality control study of parameters of leaves of Tylophora indica Brum.

The pGL3-Basic vector empty was used as a negative control, and pGL3-control vector was used for a positive control. Pieces of diaphragms were incubated with various concentrations of the crude extract for 1. The aim of this study was to evaluate whether extract of A.

The plant of Abutilon indicum is available in reach source at Melghat tiger reserve forest area.

Anti-diabetic and analgesic activity of leaves of abutilon indicum

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Pharmacognostical Evaluation of Tylophora indica Burm. The plant Cayratia carnosa gagnep. The thorax was opened, and the diaphragm was removed. The results revealed that the leaves contain steroids, sapogenins, carbohydrates and flavonoids. The distribution region plays an important determinant of pine distribution and abundance in the landscape.

Lyophilized extract was preserved in an airtight bottle at room temperature and protected from light until use.